In the Netherlands drugs are prescribed to more than 11 million patients. In clinical practice clinicians consider age, gender, allergies, organ (dys)function, comorbidity and co-medication prior to issuing a prescription. While prescribing seems ‘personalized’ to the individual patient in the traditional sense the recent breakthroughs in biomedicine have enabled the field to develop modern ways of selecting the right drug for the right patient. The session of therapeutic use will highlight recent developments of the interdisciplinary fields of pharmacy, clinical pharmacology and bio-medical sciences. The session will include a wide range of recent advances and different approaches including pharmacogenomics, re-purposing of drugs, (non-) responder analysis and novel treatment regimen.