Clinical and Translational Pharmacology

Room: BACH 1-2

Time: Monday 1st, 09:00 to 11 :00

Chair(s): Cornelis Kramers        

Organizing FIGON partner(s): Dutch Society for Clinical Pharmacology and Biopharmacy (NVKFB)

The theme of this year is “Predictive value of preclinical research for clinical pharmacology”. We start with an interesting key note lecture by Prof. Dr. Jan Danser showing the relevance of preclinical work and the translation to the clinical setting by an interesting lecture on preeclampsia and VEGF inhibitors. Since the severe side effects of VEGF inhibitors used in oncology such as hypertension and nephropathy resemble the severe complication of pregnancy preeclampsia, preclinical work using VEGF inhibitors can give important information about treatment options for preeclampsia and vice versa. This is an illustrative example of combining basic pharmacology with clinical pharmacology to optimize understanding and treatment options. This lecture is followed by four oral presentations of original research from selected abstracts showing the full scope of clinical pharmacological research performed in the Netherlands. So in this session you will find pharmacokinetic studies, translational pharmacology, personalized pharmacotherapy and pharmacoepidemiology. In conclusion, a very attractive session not to be missed by anyone interested in translational and clinical pharmacology.

Invited lecture:

09:00 – 09:40

Predictive value of preclinical research: VEGF inhibitor-induced toxicity and preeclampsia

Prof. Dr. A.H. (Jan) Danser, Erasmus MC University Medical Center, Rotterdam

Selected abstracts:

09:40 – 10:00 tbd*

10:00 – 10:20 tbd*

10:20 – 10:40 tbd*

10:40 – 11:00 tbd*

Indicated speaker time includes 5 minutes for discussion

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